Isolation and characterization of human polyreactive pneumococcal polysaccharide antibodies

Open Journal of Immunology, 2, 98-110.doi: 10.4236/oji.2012.23012. Thompson RS, Khaskhely N, Malhotra KR, Leggat D, Mosakowski J,  Khuder S, McLean GR, Westerink MA. Source Department of Medicine, University of Toledo, Toledo, OH 43614, USA. Abstract Natural antibodies serve as the body’s first line of defense against pneumococcal challenge. Polyreactive human pneumococcal polysaccharide IgG antibodies have not been extensively studied. … More Isolation and characterization of human polyreactive pneumococcal polysaccharide antibodies

Phenotypic analysis of pneumococcal polysaccharide-specific B cells

J Immunol. 2012 Mar 1;188(5):2455-63. Epub 2012 Jan 23. Khaskhely N, Mosakowski J, Thompson RS, Khuder S, Smithson SL, Westerink MA. Source Department of Medicine, University of Toledo, Toledo, OH 43614, USA. Abstract The phenotype of B cells responsible for the production of anti-pneumococcal polysaccharide Ab has been unclear. Although individuals that respond poorly to the 23-valent pneumococcal polysaccharide (PPS) vaccine, … More Phenotypic analysis of pneumococcal polysaccharide-specific B cells